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Although the primary side effects of Masteron revolve around genetic response, this hormone can potentially be very damaging to cholesterol more so than many injectable anabolic steroids. However, it should not have as strong of an effect as most oral steroids. Masteron can significantly increase LDL cholesterol (bad cholesterol) as well as significantly reduce HDL cholesterol (good cholesterol). If you suffer from high cholesterol you should not supplement with Masteron. If you are healthy enough for use, you should do all you can to promote the continuation of healthy levels. This means incorporating plenty of cardiovascular training into your routine, limiting saturated fats and simple sugars, as well as consuming plenty of omega fatty acids. Daily fish oil supplementation is highly recommended as is a cholesterol antioxidant supplement.