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Drostanolone propionate is a prodrug of drostanolone . [1] Like other AAS, drostanolone is an agonist of the androgen receptor (AR). [1] It is not a substrate for 5α-reductase and is a poor substrate for 3α-hydroxysteroid dehydrogenase (3α-HSD), and therefore shows a high ratio of anabolic to androgenic activity. [1] As a DHT derivative, drostanolone is not a substrate for aromatase and hence cannot be aromatized into estrogenic metabolites . [1] While no data are available on the progestogenic activity of drostanolone, it is thought to have low or no such activity similarly to other DHT derivatives. [1] Since the drug is not 17α-alkylated , it is not known to cause hepatotoxicity . [1]

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